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An Official American Thoracic Society Clinical Practice Guideline: Exercise-induced Bronchoconstriction

Jonathan P. Parsons, Teal S. Hallstrand, John G. Mastronarde, David A. Kaminsky, Kenneth W. Rundell, James H. Hull, William W. Storms, John M. Weiler, Fern M. Cheek, Kevin C. Wilson, and Sandra D. Anderson;
American Journal of Respiratory and Critical Care Medicine, Vol. 187, No. 9 (2013), pp. 1016-1027.

Read More: http://www.atsjournals.org/doi/abs/10.1164/rccm.201303-0437ST

Assessment of dyspnea in asthma: validation of the dyspnea-12. Yorke J, Russell AM, Swigris J, Shuldham C, Haigh C, Rochnia N, Hoyle J, Jones PW.: the journal of ashama, 2011 - 08- 48(6):602-8.


Background. Dyspnea is a prominent symptom in asthma. The Dyspnea-12 (D-12), an instrument that quantifies breathlessness using 12 descriptors that tap the physical and affective aspects, has shown promise for the measurement of dyspnea in cardiorespiratory disease. Objective. We report the results of a study designed to test the validity and reliability of the D-12 in a population of patients with asthma. Methods. This cross-sectional study included 102 patients with asthma. Subjects completed the D-12, Hospital Anxiety and Depression scale, St. George's Respiratory Questionnaire (SGRQ), and Medical Research Council scale. Confirmatory factor analysis confirmed the two-component structure of the D-12 (i.e., seven items that tap the physical aspects of breathlessness and five items that tap the affective aspects). Results. The D-12 subscales had excellent internal reliability (Cronbach's alpha for the "physical" score was 0.94 and the affective score was 0.95). The D-12 physical component was more strongly correlated with SGRQ Symptoms (r = 0.648), SGRQ Activities (r = 0.635) and Medical Research Council grade (r = 0.636), while the affective component was more strongly correlated with SGRQ Impacts (r = 0.765) and Hospital Anxiety and Depression scale scores (anxiety r = 0.641 and depression r = 0.602). Conclusion. This study supports validity of the D-12 for use in the assessment of dyspnea of patients with asthma. It assesses one of the most pertinent symptoms of asthma from two viewpoints-physical and affective.



Tne environment, the airway and the athlete. Sacha, JJ, Quin, JM. Annals of allergy, asthma & immunology, 2011, 106(2): 81-7.


The Asthmatic Athlete: Inhaled Beta-2 Agonists, Sport Performance, and Doping. Clinical Journal of Sport Medicine: January 2011 - Volume 21 - Issue 1 - pp 46-50


New therapies and management strategies in the treatment of asthma: patient-focused developments (Jan 2011)


Creatine Activates Airway Epithelium in Asthma (Int J Sports Med 2010; 31(12): 906-912)


Current recommendations for the treatment of mild asthma (Dez 2010)


Pathogenesis, prevalence, diagnosis, and management of exercise-induced bronchoconstriction: a practice parameter (Dez 2010)




Bronchial challenges and respiratory symptoms in elite swimmers and winter sport athletes: Airway hyperresponsiveness in asthma: its measurement and clinical significance (Ago 2010)




Immunological and genetic aspects of asthma and allergy (Ago 2010)


The role of the bronchial provocation challenge tests in the diagnosis of exercise-induced bronchoconstriction in elite swimmers (Ago 2010)


The impact of food allergy on asthma (Jul 2010)


The challenge of asthma in adolescent athletes: exercise induced bronchoconstriction (EIB) with and without known asthma. (Abril 2010)


Current trends in the treatment of asthma: focus on the simultaneous administration of salmeterol/fluticasone (Mar 2010)



The successful treatment of vocal cord dysfunction with low-dose amitriptyline – including literature review (Nov 2009)


An update on exercise-induced bronchoconstriction with and without asthma. (Nov 2009)


Exercise-induced asthma: critical analysis of the protective role of montelukast (Out 2009)

The protective effect of community factors on childhood asthma (Jun 2009)


Asthma in elite athletes: how do we manage asthma-like symptoms and asthma in elite athletes? (Abril 2009)


Airway hyperresponsiveness and airway inflammation in elite swimmers (Jan 2009)


Exercise-induced hypersensitivity syndromes in recreational and competitive athletes: a PRACTALL consensus report (what the general practitioner should know about sports and allergy). (Ago 2008)


Mechanisms of asthma in Olympic athletes--practical implications (Jun 2008)

Treatment of exercise-induced asthma, respiratory and allergic disorders in sports and the relationship to doping: Part II of the report from the Joint Task Force of European Respiratory Society (ERS) and European Academy of Allergy and Clinical Immunology (EAACI) in cooperation with GA(2)LEN. (Maio 2008)


Exercise-induced asthma, respiratory and allergic disorders in elite athletes: epidemiology, mechanisms and diagnosis: part I of the report from the Joint Task Force of the European Respiratory Society (ERS) and the European Academy of Allergy and Clinical Immunology (EAACI) in cooperation with GA2LEN. (Abril 2008)


Pretreatment with albuterol versus montelukast for exercise-induced bronchospasm in children (Mar 2008)


Pharmaceutical treatment of asthma symptoms in elite athletes - doping or therapy? (Dez 2007)


The use of anti-asthmatic medication among Danish elite athletes (Dez 2007)


Educational intervention decreases exhaled nitric oxide in farmers with occupational asthma (Set 2007)


Do inhaled beta(2)-agonists have an ergogenic potential in non-asthmatic competitive athletes? (Fev 2007)


Is there a problem with inhaled long-acting beta-adrenergic agonists? (Jan 2006)


Is asthma over- or under-diagnosed in athletes? (Fev 2003)




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